Diethylenediamine (anhydrous piperazine)-product synthesis technology transfer
【1】Product name and introduction
Structural formula.
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Chinese Name |
Piperazine; Diethylenediamine; Anhydrous piperazine; p-Diazocyclohexane; Diethylenediamine; Bis(dimethylamine) Perphenazine; Tetramethylenediamine; p-Diazocyclohexane |
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English Name |
Piperazine；Piperazine anhydrous; Diethylene diamine;1,4-Diazacyclohexane;piperazinediium |
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Molecular Formula |
C4H10N2 |
Appearance |
Colorless transparent needle-like or leaf-like crystals |
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Molecular weight |
86.1356 |
EINECS |
203-808-3 |
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CAS |
110-85-0 |
CB Number |
CB5852824 |
【2】Product usage
- Piperazine is an important pharmaceutical intermediate, mainly used in the production of anthelmintic piperazine phosphate, piperazine citrate and fluphenazine, prednisone, rifampicin, piperazine adipate, guanfacine, methyltetracycline, quinpiaphosphate, perphenazine, enoxacin, hydroxyzine hydrochloride, trifluoperazine, ethamazine citrate, guilizine, flunarizine, dechloroxazine, prednisidine, sodium hydrogenated prednisone phosphate, sodium dexamethasone phosphate, pyrimethamine, norfloxacin, ciprofloxacin, e-coughazine, meperidine, trimethoprim and other drugs.
- Also used in the production of surfactant products such as wetting agents, emulsifiers and dispersants.
- Production of antioxidants, preservatives, stabilizers and other plastic processing aids and rubber additives.
- Downstream products:N-methylpiperazine, N-benzylpiperazine, norfloxacin, piperaquine phosphate, piperazine citrate, flunarizine hydrochloride
Synthesis Introduction
This synthesis process is produced in a kettle-type intermittent production with commercially available catalysts.
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